Formerly known as Potgietersrus, Mokopane and its surrounds have a multitude of historical and cultural features. The archaeological site of the MakapansValley has records of hominid life going back3,3 million yeas.

The Cave of Hearths, once the site of bloody confrontations between the Voortrekkers and BaTlou people, has a sequence of artifacts dating from the Early Stone Age throught to the Late Stone Age.

The Arend Dieperink Museum covers the history of the town, with features ranging from Bushman drawings to the modern day. Mokopane's major industries inclue mining and agriculture.

The nearby Zebediela Citrus Estate is the largest citrus farm on the Southern Hemisphere. A game breading centre belonging to the National Zoological gardens of Africa on the northern border of the town makes for an excellent family outing.